Symbol
Name
ID

Mecp2
methyl CpG binding protein 2
MGI:99918

Phenotype annotations related to respiratory system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Recurrent respiratory infections	Apnea	Intermittent hyperventilation	Central hypoventilation	Aspiration	Respiratory insufficiency
Disease(s) Associated with MECP2	Recurrent respiratory infections	Apnea	Intermittent hyperventilation	Central hypoventilation	Aspiration	Respiratory insufficiency
Rett syndrome
severe congenital encephalopathy due to MECP2 mutation
syndromic X-linked intellectual disability Lubs type
X-linked intellectual disability-psychosis-macroorchidism syndrome

Mouse Phenotypes		respiratory system phenotype	abnormal respiration	decreased tidal volume	abnormal breathing pattern	increased pulmonary respiratory rate	tachypnea	apnea	respiratory distress	decreased respiration
Availability	Mouse Genotype	respiratory system phenotype	abnormal respiration	decreased tidal volume	abnormal breathing pattern	increased pulmonary respiratory rate	tachypnea	apnea	respiratory distress	decreased respiration
	Mecp2^tm1.1Bird/Mecp2^tm1.1Bird
	Mecp2^tm1.1Jtc/Mecp2^tm1.1Jtc
	Mecp2^tm1.1Bird/Mecp2⁺
	Mecp2^tm1.1Irsf/Mecp2⁺
	Mecp2^tm1.1Jae/Mecp2⁺
	Mecp2^tm2Bird/Mecp2⁺
	Mecp2^em1Jlzn/Y
	Mecp2^tm1.1Bird/Y
	Mecp2^tm1.1Irsf/Y
	Mecp2^tm1.1Jae/Y
	Mecp2^tm1.1Jtc/Y
	Mecp2^tm1Bird/Y	*
	Mecp2^tm1Pplt/Y
	Mecp2^tm2Bird/Y
	Mecp2^tm1Jae/Y Chat^tm2(cre)Lowl/Chat⁺ (conditional)	*
	Chat^tm2(cre)Lowl/Chat⁺ Mecp2^tm2Bird/Y (conditional)
	Mecp2^tm2Bird/Mecp2⁺ Tg(CAG-cre/Esr1*)5Amc/? (conditional)
	Mecp2^tm1Bird/Y Tg(dlx5a-cre)1Mekk/0 (conditional)	*
	Mecp2^tm1Bird/Y Tg(Slc32a1-cre)2.1Hzo/0 (conditional)
	Mecp2^tm1Jae/Y Tg(Nes-cre)1Atp/0 (conditional)
	Mecp2^tm2Bird/Y Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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